The companies have been embroiled in a row about compounded GLP-1 drugs that escalated to a lawsuit last month
Furthermore, a network meta-analysis examining the effects of GLP-1 RA therapy on body composition reported a greater reduction in lean body mass in the intervention group compared with placebo or active comparators (mean difference = 0.86 kg, 95%CI: 1.30, 0.42)
Instead, some med-spas, telehealth companies, and compounding entities have continued compounding or supplying GLP-1s frequently sourcing active pharmaceutical ingredients, or APIs, from abroad, sometimes via unregulated importers
Such side effects are usually mild to moderate in severity and tend to decrease over time as the body adjusts to the medication
They do not need to be monitored, encouraged to eat more, reminded of protein targets at every meal, or celebrated every time they make a particular food choice